Preliminary phytochemical screening and antibacterial properties of crude stem bark extracts and fractions of Parkia biglobosa (Jacq.).

نویسندگان

  • Emmanuel O Abioye
  • David A Akinpelu
  • Olayinka A Aiyegoro
  • Mobolaji F Adegboye
  • Matthew O Oni
  • Anthony I Okoh
چکیده

A methanolic crude extract of Parkia biglobosa was prepared and later partitioned in succession with different solvents of increasing polarity ranging from n-hexane, chloroform and ethyl acetate to butanol. Phytochemical screening of the extract revealed the presence of alkaloids, tannins, saponins, flavonoids, steroids, glycoside and sugars. The inhibition zones exhibited by the extract against the tested bacteria ranged between 14 ± 0.00 mm (against Escherichia coli) and 28 ± 0.71 mm (against Pseudomonas aeruginosa). The MIC of the methanolic extract of P. biglobosa against isolates ranged between 0.63 mg/mL and 5 mg/mL, while the MIC values exhibited by the n-hexane and aqueous fractions ranged between 0.63 mg/mL and 10 mg/mL. Overall the extract and fractions of P. biglobosa used in this work were found to possess antimicrobial properties which compared favourably with those of streptomycin. These observations make this plant a potential source of bioactive compounds that can be used in management of bacterial infections. The use of this plant as herbal medicaments in African countries and the reports on the toxicity of the plant further show that the plant is non-toxic to humans.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Comparative study of leaf and stem bark extracts of Parkia biglobosa against enterobacteria.

Hydroethanolic and aqueous extracts of leaf and stem bark of Parkia biglobosa (Jacq) Benth. (Mimosaceae) were tested against clinical isolates Escherichia coli, Salmonella typhi, Shigella dysenteriae and Enterococcus faecalis, and corresponding collection strains E. coli CIP 105 182, Salmonella enterica CIP 105 150, Shigella dysenteriae CIP 54-51 and Enterococcus faecalis CIP 103 907. Discs of ...

متن کامل

Phytochemical and Antibacterial Properties of Parkia Biglobosa and Parkia Bicolor Leaf Extracts Ajaiyeoba,

The comparative studies of different extracts of the leaves of Parkia biglobosa (Jacq) Benth and Parkia bicolor A. Chev (Mimosaceae) with respect to their photochemical and antimicrobial properties was carried out. Preliminary phytochemical screening showed that both plants had similar constituents namely cardiac glycosides, steroids, tannins and alkaloids. The thin layer chromatography of the ...

متن کامل

Comparative Study of Leaf and Stem Bark Extracts of Parkia Biglobosa against Enterobacteria

Hydroethanolic and aqueous extracts of leaf and stem bark of Parkia biglobosa (Jacq) Benth. (Mimosaceae) were tested against clinical isolates Escherichia coli, Salmonella typhi, Shigella dysenteriae and Enterococcus faecalis, and corresponding collection strains E. coli CIP 105 182, Salmonella enterica CIP 105 150, Shigella dysenteriae CIP 54-51 and Enterococcus faecalis CIP 103 907. Discs of ...

متن کامل

Antimicrobial effects of the stem bark extracts of Parkia biglobosa (Jacq.) Benth. on Shigellae.

Total and hydroalcoholic extracts of the stem barks of Parkia biglobosa (Jacq) Benth. (Mimosaceae) were tested on strains belonging to three species of Shigellae: S. dysenteriae, S. flexneri and S. boydii collected from hospitals in Ouagadougou, Burkina Faso. The results showed that both extracts were active against Shigellae. The hydroalcoholic extract was more active than the decoction (aqueo...

متن کامل

Effects of Methanol Extract of Parkia biglobosa Stem Bark on the Liver and Kidney Functions of Albino Rats

Extract of Parkia biglobosa stem bark is used in treating of malaria, diarrhoea, pains and host of other diseases in Nigerian traditional medicine (NTM). The aim of this research was to determine the beneficial properties of Parkia biglobosa as drug and its effect on the vital organs (such as liver and kidney). To achieve this, parameters such as ALP, ALT, AST, catalase, urea, PCV, RBC count, M...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Molecules

دوره 18 7  شماره 

صفحات  -

تاریخ انتشار 2013